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Bacterial Nitric Oxide Synthase Is Required for the Staphylococcus aureus Response to Heme Stress

Staphylococcus aureus is a pathogen that causes significant morbidity and mortality worldwide. Within the vertebrate host, S. aureus requires heme as a nutrient iron source and as a cofactor for multiple cellular processes. Although required for pathogenesis, excess heme is toxic. S. aureus employs...

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Bibliografiske detaljer
Udgivet i:ACS Infect Dis
Main Authors: Surdel, Matthew C., Dutter, Brendan F., Sulikowski, Gary A., Skaar, Eric P.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610873/
https://ncbi.nlm.nih.gov/pubmed/27626297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00081
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