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Decoupling Activation of Heme Biosynthesis from Anaerobic Toxicity in a Molecule Active in Staphylococcus aureus

Small molecules active in the pathogenic bacterium Staphylococcus aureus are valuable tools for the study of its basic biology and pathogenesis, and many molecules may provide leads for novel therapeutics. We have previously reported a small molecule, 1, which activates endogenous heme biosynthesis...

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Publicat a:ACS Chem Biol
Autors principals: Dutter, Brendan F., Mike, Laura A., Reid, Paul R., Chong, Katherine M., Ramos-Hunter, Susan J., Skaar, Eric P., Sulikowski, Gary A.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117894/
https://ncbi.nlm.nih.gov/pubmed/26890615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00934
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