Insulin receptor isoform A ameliorates long-term glucose intolerance in diabetic mice

Type 2 diabetes mellitus is a complex metabolic disease and its pathogenesis involves abnormalities in both peripheral insulin action and insulin secretion. Previous in vitro data showed that insulin receptor isoform A, but not B, favours basal glucose uptake through its specific association with en...

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Bibliographic Details
Published in:Dis Model Mech
Main Authors: Diaz-Castroverde, Sabela, Gómez-Hernández, Almudena, Fernández, Silvia, García-Gómez, Gema, Di Scala, Marianna, González-Aseguinolaza, Gloria, Fernández-Millán, Elisa, González-Rodríguez, Águeda, García-Bravo, María, Chambon, Pierre, Álvarez, Carmen, Perdomo, Liliana, Beneit, Nuria, Escribano, Oscar, Benito, Manuel
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117224/
https://ncbi.nlm.nih.gov/pubmed/27562101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.025288
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