Insulin receptor isoform A ameliorates long-term glucose intolerance in diabetic mice

Type 2 diabetes mellitus is a complex metabolic disease and its pathogenesis involves abnormalities in both peripheral insulin action and insulin secretion. Previous in vitro data showed that insulin receptor isoform A, but not B, favours basal glucose uptake through its specific association with en...

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Bibliografische gegevens
Gepubliceerd in:Dis Model Mech
Hoofdauteurs: Diaz-Castroverde, Sabela, Gómez-Hernández, Almudena, Fernández, Silvia, García-Gómez, Gema, Di Scala, Marianna, González-Aseguinolaza, Gloria, Fernández-Millán, Elisa, González-Rodríguez, Águeda, García-Bravo, María, Chambon, Pierre, Álvarez, Carmen, Perdomo, Liliana, Beneit, Nuria, Escribano, Oscar, Benito, Manuel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists Ltd 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117224/
https://ncbi.nlm.nih.gov/pubmed/27562101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.025288
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