Insulin receptor isoform A ameliorates long-term glucose intolerance in diabetic mice

Type 2 diabetes mellitus is a complex metabolic disease and its pathogenesis involves abnormalities in both peripheral insulin action and insulin secretion. Previous in vitro data showed that insulin receptor isoform A, but not B, favours basal glucose uptake through its specific association with en...

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Vydáno v:Dis Model Mech
Hlavní autoři: Diaz-Castroverde, Sabela, Gómez-Hernández, Almudena, Fernández, Silvia, García-Gómez, Gema, Di Scala, Marianna, González-Aseguinolaza, Gloria, Fernández-Millán, Elisa, González-Rodríguez, Águeda, García-Bravo, María, Chambon, Pierre, Álvarez, Carmen, Perdomo, Liliana, Beneit, Nuria, Escribano, Oscar, Benito, Manuel
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117224/
https://ncbi.nlm.nih.gov/pubmed/27562101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.025288
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