Insulin receptor isoform A ameliorates long-term glucose intolerance in diabetic mice

Type 2 diabetes mellitus is a complex metabolic disease and its pathogenesis involves abnormalities in both peripheral insulin action and insulin secretion. Previous in vitro data showed that insulin receptor isoform A, but not B, favours basal glucose uptake through its specific association with en...

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Enregistré dans:
Détails bibliographiques
Publié dans:Dis Model Mech
Auteurs principaux: Diaz-Castroverde, Sabela, Gómez-Hernández, Almudena, Fernández, Silvia, García-Gómez, Gema, Di Scala, Marianna, González-Aseguinolaza, Gloria, Fernández-Millán, Elisa, González-Rodríguez, Águeda, García-Bravo, María, Chambon, Pierre, Álvarez, Carmen, Perdomo, Liliana, Beneit, Nuria, Escribano, Oscar, Benito, Manuel
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117224/
https://ncbi.nlm.nih.gov/pubmed/27562101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.025288
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