Potential role of insulin receptor isoforms and IGF receptors in plaque instability of human and experimental atherosclerosis

BACKGROUND: Clinical complications associated with atherosclerotic plaques arise from luminal obstruction due to plaque growth or destabilization leading to rupture. We previously demonstrated that overexpression of insulin receptor isoform A (IRA) and insulin-like growth factor-I receptor (IGF-IR)...

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Bibliographic Details
Published in:Cardiovasc Diabetol
Main Authors: Beneit, Nuria, Martín-Ventura, José Luis, Rubio-Longás, Carlota, Escribano, Óscar, García-Gómez, Gema, Fernández, Silvia, Sesti, Giorgio, Hribal, Marta Letizia, Egido, Jesús, Gómez-Hernández, Almudena, Benito, Manuel
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
Subjects:
Original Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819698/
https://ncbi.nlm.nih.gov/pubmed/29463262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-018-0675-2
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