The Role of Insulin Receptor Isoforms in Diabetes and Its Metabolic and Vascular Complications

The insulin receptor (IR) presents by alternative splicing two isoforms: IRA and IRB. The differential physiological and pathological role of both isoforms is not completely known, and it is determinant the different binding affinity for insulin-like growth factor. IRB is more abundant in adult tiss...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Escribano, O., Beneit, N., Rubio-Longás, C., López-Pastor, A. R., Gómez-Hernández, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5671728/
https://ncbi.nlm.nih.gov/pubmed/29201918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/1403206
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