Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal

Sox2 marks dental epithelial stem cells (DESCs) in both mammals and reptiles, and in this article we demonstrate several Sox2 transcriptional mechanisms that regulate dental stem cell fate and incisor growth. Conditional Sox2 deletion in the oral and dental epithelium results in severe craniofacial...

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Dades bibliogràfiques
Publicat a:Development
Autors principals: Sun, Zhao, Yu, Wenjie, Sanz Navarro, Maria, Sweat, Mason, Eliason, Steven, Sharp, Thad, Liu, Huan, Seidel, Kerstin, Zhang, Li, Moreno, Myriam, Lynch, Thomas, Holton, Nathan E., Rogers, Laura, Neff, Traci, Goodheart, Michael J., Michon, Frederic, Klein, Ophir D., Chai, Yang, Dupuy, Adam, Engelhardt, John F., Chen, Zhi, Amendt, Brad A.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2016
Matèries:
Stem Cells and Regeneration
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117215/
https://ncbi.nlm.nih.gov/pubmed/27660324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.138883
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