Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal

Sox2 marks dental epithelial stem cells (DESCs) in both mammals and reptiles, and in this article we demonstrate several Sox2 transcriptional mechanisms that regulate dental stem cell fate and incisor growth. Conditional Sox2 deletion in the oral and dental epithelium results in severe craniofacial...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Sun, Zhao, Yu, Wenjie, Sanz Navarro, Maria, Sweat, Mason, Eliason, Steven, Sharp, Thad, Liu, Huan, Seidel, Kerstin, Zhang, Li, Moreno, Myriam, Lynch, Thomas, Holton, Nathan E., Rogers, Laura, Neff, Traci, Goodheart, Michael J., Michon, Frederic, Klein, Ophir D., Chai, Yang, Dupuy, Adam, Engelhardt, John F., Chen, Zhi, Amendt, Brad A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Stem Cells and Regeneration
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117215/
https://ncbi.nlm.nih.gov/pubmed/27660324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.138883
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