Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal

Sox2 marks dental epithelial stem cells (DESCs) in both mammals and reptiles, and in this article we demonstrate several Sox2 transcriptional mechanisms that regulate dental stem cell fate and incisor growth. Conditional Sox2 deletion in the oral and dental epithelium results in severe craniofacial...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Development
Egile Nagusiak: Sun, Zhao, Yu, Wenjie, Sanz Navarro, Maria, Sweat, Mason, Eliason, Steven, Sharp, Thad, Liu, Huan, Seidel, Kerstin, Zhang, Li, Moreno, Myriam, Lynch, Thomas, Holton, Nathan E., Rogers, Laura, Neff, Traci, Goodheart, Michael J., Michon, Frederic, Klein, Ophir D., Chai, Yang, Dupuy, Adam, Engelhardt, John F., Chen, Zhi, Amendt, Brad A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists Ltd 2016
Gaiak:
Stem Cells and Regeneration
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117215/
https://ncbi.nlm.nih.gov/pubmed/27660324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.138883
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