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PITX2 and β-Catenin Interactions Regulate Lef-1 Isoform Expression
Lef-1 and PITX2 function in the Wnt signaling pathway by recruiting and interacting with β-catenin to activate target genes. Chromatin immunoprecipitation (ChIP) assays identified the Lef-1 promoter as a PITX2 downstream target. Transgenic mice expressing LacZ driven by the 2.5-kb LEF-1 promoter dem...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2169058/ https://ncbi.nlm.nih.gov/pubmed/17785445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00315-07 |
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