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Ectodermal Organ Development Is Regulated by a microRNA-26b-Lef-1-Wnt Signaling Axis

The developmental role of Lef-1 in ectodermal organs has been characterized using Lef-1 murine knockout models. We generated a Lef-1 conditional over-expression (COEL) mouse to determine the role of Lef-1 expression in epithelial structures at later stages of development after endogenous expression...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Eliason, Steve, Sharp, Thad, Sweat, Mason, Sweat, Yan Y., Amendt, Brad A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372039/
https://ncbi.nlm.nih.gov/pubmed/32760291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00780
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