Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal

Sox2 marks dental epithelial stem cells (DESCs) in both mammals and reptiles, and in this article we demonstrate several Sox2 transcriptional mechanisms that regulate dental stem cell fate and incisor growth. Conditional Sox2 deletion in the oral and dental epithelium results in severe craniofacial...

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Bibliografiske detaljer
Udgivet i:Development
Main Authors: Sun, Zhao, Yu, Wenjie, Sanz Navarro, Maria, Sweat, Mason, Eliason, Steven, Sharp, Thad, Liu, Huan, Seidel, Kerstin, Zhang, Li, Moreno, Myriam, Lynch, Thomas, Holton, Nathan E., Rogers, Laura, Neff, Traci, Goodheart, Michael J., Michon, Frederic, Klein, Ophir D., Chai, Yang, Dupuy, Adam, Engelhardt, John F., Chen, Zhi, Amendt, Brad A.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2016
Fag:
Stem Cells and Regeneration
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117215/
https://ncbi.nlm.nih.gov/pubmed/27660324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.138883
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