Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal

Sox2 marks dental epithelial stem cells (DESCs) in both mammals and reptiles, and in this article we demonstrate several Sox2 transcriptional mechanisms that regulate dental stem cell fate and incisor growth. Conditional Sox2 deletion in the oral and dental epithelium results in severe craniofacial...

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Podrobná bibliografie
Vydáno v:Development
Hlavní autoři: Sun, Zhao, Yu, Wenjie, Sanz Navarro, Maria, Sweat, Mason, Eliason, Steven, Sharp, Thad, Liu, Huan, Seidel, Kerstin, Zhang, Li, Moreno, Myriam, Lynch, Thomas, Holton, Nathan E., Rogers, Laura, Neff, Traci, Goodheart, Michael J., Michon, Frederic, Klein, Ophir D., Chai, Yang, Dupuy, Adam, Engelhardt, John F., Chen, Zhi, Amendt, Brad A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2016
Témata:
Stem Cells and Regeneration
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117215/
https://ncbi.nlm.nih.gov/pubmed/27660324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.138883
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