Immunization with outer membrane vesicles displaying designer glycotopes yields class-switched, glycan-specific antibodies

The development of antibodies against specific glycan epitopes poses a significant challenge due to difficulties obtaining desired glycans at sufficient quantity and purity, and the fact that glycans are usually weakly immunogenic. To address this challenge, we leveraged the potent immunostimulatory...

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Bibliografske podrobnosti
izdano v:Cell Chem Biol
Main Authors: Valentine, Jenny L., Chen, Linxiao, Perregaux, Emily C., Weyant, Kevin B., Rosenthal, Joseph A., Heiss, Christian, Azadi, Parastoo, Fisher, Adam C., Putnam, David, Moe, Gregory R., Merritt, Judith H., DeLisa, Matthew P.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116915/
https://ncbi.nlm.nih.gov/pubmed/27341433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2016.05.014
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