Immunization with outer membrane vesicles displaying designer glycotopes yields class-switched, glycan-specific antibodies

The development of antibodies against specific glycan epitopes poses a significant challenge due to difficulties obtaining desired glycans at sufficient quantity and purity, and the fact that glycans are usually weakly immunogenic. To address this challenge, we leveraged the potent immunostimulatory...

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Detaylı Bibliyografya
Yayımlandı:Cell Chem Biol
Asıl Yazarlar: Valentine, Jenny L., Chen, Linxiao, Perregaux, Emily C., Weyant, Kevin B., Rosenthal, Joseph A., Heiss, Christian, Azadi, Parastoo, Fisher, Adam C., Putnam, David, Moe, Gregory R., Merritt, Judith H., DeLisa, Matthew P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116915/
https://ncbi.nlm.nih.gov/pubmed/27341433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2016.05.014
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