TET-dependent regulation of retrotransposable elements in mouse embryonic stem cells

BACKGROUND: Ten-eleven translocation (TET) enzymes oxidise DNA methylation as part of an active demethylation pathway. Despite extensive research into the role of TETs in genome regulation, little is known about their effect on transposable elements (TEs), which make up nearly half of the mouse and...

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Vydáno v:Genome Biol
Hlavní autoři: de la Rica, Lorenzo, Deniz, Özgen, Cheng, Kevin C. L., Todd, Christopher D., Cruz, Cristina, Houseley, Jonathan, Branco, Miguel R.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116139/
https://ncbi.nlm.nih.gov/pubmed/27863519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1096-8
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