CFTR controls biliary epithelial inflammation and permeability by regulating Src tyrosine kinase activity

In the liver, CFTR regulates bile secretion and other functions at the apical membrane of biliary epithelial cells (i.e cholangiocytes). CF-related liver disease (CFLD) is a major cause of death in patients with CF. CFTR dysfunction affects innate immune pathways, generating a para-inflammatory stat...

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Vydáno v:Hepatology
Hlavní autoři: Fiorotto, Romina, Villani, Ambra, Kourtidis, Antonis, Scirpo, Roberto, Amenduni, Mariangela, Geibel, Peter J., Cadamuro, Massimilano, Spirli, Carlo, Anastasiadis, Panos Z., Strazzabosco, Mario
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115965/
https://ncbi.nlm.nih.gov/pubmed/27629435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28817
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