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CFTR controls biliary epithelial inflammation and permeability by regulating Src tyrosine kinase activity
In the liver, CFTR regulates bile secretion and other functions at the apical membrane of biliary epithelial cells (i.e cholangiocytes). CF-related liver disease (CFLD) is a major cause of death in patients with CF. CFTR dysfunction affects innate immune pathways, generating a para-inflammatory stat...
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| Publicado no: | Hepatology |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5115965/ https://ncbi.nlm.nih.gov/pubmed/27629435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28817 |
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