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Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures

BACKGROUND: Tumor-infiltrating immune cells have been linked to prognosis and response to immunotherapy; however, the levels of distinct immune cell subsets and the signals that draw them into a tumor, such as the expression of antigen presenting machinery genes, remain poorly characterized. Here, w...

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Vydáno v:Genome Biol
Hlavní autoři: Şenbabaoğlu, Yasin, Gejman, Ron S., Winer, Andrew G., Liu, Ming, Van Allen, Eliezer M., de Velasco, Guillermo, Miao, Diana, Ostrovnaya, Irina, Drill, Esther, Luna, Augustin, Weinhold, Nils, Lee, William, Manley, Brandon J., Khalil, Danny N., Kaffenberger, Samuel D., Chen, Yingbei, Danilova, Ludmila, Voss, Martin H., Coleman, Jonathan A., Russo, Paul, Reuter, Victor E., Chan, Timothy A., Cheng, Emily H., Scheinberg, David A., Li, Ming O., Choueiri, Toni K., Hsieh, James J., Sander, Chris, Hakimi, A. Ari
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114739/
https://ncbi.nlm.nih.gov/pubmed/27855702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1092-z
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