Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures

BACKGROUND: Tumor-infiltrating immune cells have been linked to prognosis and response to immunotherapy; however, the levels of distinct immune cell subsets and the signals that draw them into a tumor, such as the expression of antigen presenting machinery genes, remain poorly characterized. Here, w...

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Bibliografiska uppgifter
I publikationen:Genome Biol
Huvudupphovsmän: Şenbabaoğlu, Yasin, Gejman, Ron S., Winer, Andrew G., Liu, Ming, Van Allen, Eliezer M., de Velasco, Guillermo, Miao, Diana, Ostrovnaya, Irina, Drill, Esther, Luna, Augustin, Weinhold, Nils, Lee, William, Manley, Brandon J., Khalil, Danny N., Kaffenberger, Samuel D., Chen, Yingbei, Danilova, Ludmila, Voss, Martin H., Coleman, Jonathan A., Russo, Paul, Reuter, Victor E., Chan, Timothy A., Cheng, Emily H., Scheinberg, David A., Li, Ming O., Choueiri, Toni K., Hsieh, James J., Sander, Chris, Hakimi, A. Ari
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114739/
https://ncbi.nlm.nih.gov/pubmed/27855702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1092-z
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