Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures

BACKGROUND: Tumor-infiltrating immune cells have been linked to prognosis and response to immunotherapy; however, the levels of distinct immune cell subsets and the signals that draw them into a tumor, such as the expression of antigen presenting machinery genes, remain poorly characterized. Here, w...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Şenbabaoğlu, Yasin, Gejman, Ron S., Winer, Andrew G., Liu, Ming, Van Allen, Eliezer M., de Velasco, Guillermo, Miao, Diana, Ostrovnaya, Irina, Drill, Esther, Luna, Augustin, Weinhold, Nils, Lee, William, Manley, Brandon J., Khalil, Danny N., Kaffenberger, Samuel D., Chen, Yingbei, Danilova, Ludmila, Voss, Martin H., Coleman, Jonathan A., Russo, Paul, Reuter, Victor E., Chan, Timothy A., Cheng, Emily H., Scheinberg, David A., Li, Ming O., Choueiri, Toni K., Hsieh, James J., Sander, Chris, Hakimi, A. Ari
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114739/
https://ncbi.nlm.nih.gov/pubmed/27855702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1092-z
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