Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures

BACKGROUND: Tumor-infiltrating immune cells have been linked to prognosis and response to immunotherapy; however, the levels of distinct immune cell subsets and the signals that draw them into a tumor, such as the expression of antigen presenting machinery genes, remain poorly characterized. Here, w...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Şenbabaoğlu, Yasin, Gejman, Ron S., Winer, Andrew G., Liu, Ming, Van Allen, Eliezer M., de Velasco, Guillermo, Miao, Diana, Ostrovnaya, Irina, Drill, Esther, Luna, Augustin, Weinhold, Nils, Lee, William, Manley, Brandon J., Khalil, Danny N., Kaffenberger, Samuel D., Chen, Yingbei, Danilova, Ludmila, Voss, Martin H., Coleman, Jonathan A., Russo, Paul, Reuter, Victor E., Chan, Timothy A., Cheng, Emily H., Scheinberg, David A., Li, Ming O., Choueiri, Toni K., Hsieh, James J., Sander, Chris, Hakimi, A. Ari
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114739/
https://ncbi.nlm.nih.gov/pubmed/27855702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1092-z
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