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DNA polymerase θ (POLQ), double-strand break repair, and cancer
DNA polymerase theta (pol θ) is encoded in the genomes of many eukaryotes, though not in fungi. Pol θ is encoded by the POLQ gene in mammalian cells. The C-terminal third of the protein is a family A DNA polymerase with additional insertion elements relative to prokaryotic homologs. The N-terminal t...
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| 出版年: | DNA Repair (Amst) |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5114520/ https://ncbi.nlm.nih.gov/pubmed/27264557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.05.003 |
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