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Lesion bypass activity of DNA polymerase θ (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts
POLQ (polθ) is a large, multi-domain DNA polymerase0020encoded in higher eukaryotic genomes. It is important for maintaining genetic stability in cells and helping protect cells from DNA damage caused by ionizing radiation. POLQ contains an N-terminal helicase-like domain, a large central domain of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025778/ https://ncbi.nlm.nih.gov/pubmed/21050863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.10.041 |
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