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DNA polymerase θ (POLQ) can extend from mismatches and from bases opposite a (6–4) photoproduct
DNA polymerase θ (pol θ) is a nuclear A-family DNA polymerase encoded by the POLQ gene in vertebrate cells. The biochemical properties of pol θ and of Polq-defective mice have suggested that pol θ participates in DNA damage tolerance. For example, pol θ was previously found to be proficient not only...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2185714/ https://ncbi.nlm.nih.gov/pubmed/17920341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.08.005 |
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