Loss of ift122, a Retrograde Intraflagellar Transport (IFT) Complex Component, Leads to Slow, Progressive Photoreceptor Degeneration Due to Inefficient Opsin Transport

In the retina, aberrant opsin transport from cell bodies to outer segments leads to retinal degenerative diseases such as retinitis pigmentosa. Opsin transport is facilitated by the intraflagellar transport (IFT) system that mediates the bidirectional movement of proteins within cilia. In contrast t...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Boubakri, Meriam, Chaya, Taro, Hirata, Hiromi, Kajimura, Naoko, Kuwahara, Ryusuke, Ueno, Akiko, Malicki, Jarema, Furukawa, Takahisa, Omori, Yoshihiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Molecular Bases of Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114401/
https://ncbi.nlm.nih.gov/pubmed/27681595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.738658
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi