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The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance

Approximately 10% of the photoreceptor outer segment (OS) is turned over each day, requiring large amounts of lipid and protein to be moved from the inner segment to the OS. Defects in intraphotoreceptor transport can lead to retinal degeneration and blindness. The transport mechanisms are unknown,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pazour, Gregory J., Baker, Sheila A., Deane, James A., Cole, Douglas G., Dickert, Bethany L., Rosenbaum, Joel L., Witman, George B., Besharse, Joseph C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2002
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173265/
https://ncbi.nlm.nih.gov/pubmed/11916979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200107108
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