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The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance

Approximately 10% of the photoreceptor outer segment (OS) is turned over each day, requiring large amounts of lipid and protein to be moved from the inner segment to the OS. Defects in intraphotoreceptor transport can lead to retinal degeneration and blindness. The transport mechanisms are unknown,...

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Библиографические подробности
Главные авторы: Pazour, Gregory J., Baker, Sheila A., Deane, James A., Cole, Douglas G., Dickert, Bethany L., Rosenbaum, Joel L., Witman, George B., Besharse, Joseph C.
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2002
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173265/
https://ncbi.nlm.nih.gov/pubmed/11916979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200107108
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