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The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance

Approximately 10% of the photoreceptor outer segment (OS) is turned over each day, requiring large amounts of lipid and protein to be moved from the inner segment to the OS. Defects in intraphotoreceptor transport can lead to retinal degeneration and blindness. The transport mechanisms are unknown,...

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Autores principales: Pazour, Gregory J., Baker, Sheila A., Deane, James A., Cole, Douglas G., Dickert, Bethany L., Rosenbaum, Joel L., Witman, George B., Besharse, Joseph C.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173265/
https://ncbi.nlm.nih.gov/pubmed/11916979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200107108
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