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CXCL12 retargeting of an adenovirus vector to cancer cells using a bispecific adapter

Ad vectors are promising delivery vehicles for cancer therapeutic interventions. However, their application is limited by promiscuous tissue tropism and hepatotoxicity. This limitation can be avoided by altering the native tropism of Ads so that they can be redirected to the target cells through alt...

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Detalhes bibliográficos
Publicado no:Oncolytic Virother
Main Authors: Bhatia, Shilpa, O’Bryan, Samia M, Rivera, Angel A, Curiel, David T, Mathis, J Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113939/
https://ncbi.nlm.nih.gov/pubmed/27957479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OV.S112107
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