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CXCL12 retargeting of an adenovirus vector to cancer cells using a bispecific adapter

Ad vectors are promising delivery vehicles for cancer therapeutic interventions. However, their application is limited by promiscuous tissue tropism and hepatotoxicity. This limitation can be avoided by altering the native tropism of Ads so that they can be redirected to the target cells through alt...

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書目詳細資料
發表在:Oncolytic Virother
Main Authors: Bhatia, Shilpa, O’Bryan, Samia M, Rivera, Angel A, Curiel, David T, Mathis, J Michael
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113939/
https://ncbi.nlm.nih.gov/pubmed/27957479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OV.S112107
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