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CXCL12 retargeting of an adenovirus vector to cancer cells using a bispecific adapter

Ad vectors are promising delivery vehicles for cancer therapeutic interventions. However, their application is limited by promiscuous tissue tropism and hepatotoxicity. This limitation can be avoided by altering the native tropism of Ads so that they can be redirected to the target cells through alt...

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Podrobná bibliografie
Vydáno v:Oncolytic Virother
Hlavní autoři: Bhatia, Shilpa, O’Bryan, Samia M, Rivera, Angel A, Curiel, David T, Mathis, J Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113939/
https://ncbi.nlm.nih.gov/pubmed/27957479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OV.S112107
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