Double gene siRNA knockdown of mutant p53 and TNF induces apoptosis in triple-negative breast cancer cells

Apoptosis is the major downregulated pathway in cancer. Simultaneous inhibition using specific small interfering RNA (siRNA) of two key player genes, p53 and TNF, is an interesting and feasible strategy when it comes to investigating various molecular pathways and biological processes in triple-nega...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Onco Targets Ther
Prif Awduron: Pileczki, Valentina, Pop, Laura, Braicu, Cornelia, Budisan, Livia, Bolba Morar, Gabriela, del C Monroig-Bosque, Paloma, Sandulescu, Robert V, Berindan-Neagoe, Ioana
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2016
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113913/
https://ncbi.nlm.nih.gov/pubmed/27956838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S110719
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