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p53 siRNA - a therapeutic tool with significant implication in the modulation of apoptosis and angiogenic pathways
BACKGROUND AND AIMS: siRNAs represent an encouraging novel alternative in cancer therapy as a result of targeting the mutated tumour suppressor genes or activated oncogenes. Targeting oncogenic signals, as the mutated p53 gene that gains oncogenic role, we observed inhibition of migration, a downreg...
Uloženo v:
| Vydáno v: | Clujul Med |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Iuliu Hatieganu University of Medicine and Pharmacy
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4632892/ https://ncbi.nlm.nih.gov/pubmed/26609266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15386/cjmed-434 |
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