Double gene siRNA knockdown of mutant p53 and TNF induces apoptosis in triple-negative breast cancer cells

Apoptosis is the major downregulated pathway in cancer. Simultaneous inhibition using specific small interfering RNA (siRNA) of two key player genes, p53 and TNF, is an interesting and feasible strategy when it comes to investigating various molecular pathways and biological processes in triple-nega...

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Foilsithe in:Onco Targets Ther
Main Authors: Pileczki, Valentina, Pop, Laura, Braicu, Cornelia, Budisan, Livia, Bolba Morar, Gabriela, del C Monroig-Bosque, Paloma, Sandulescu, Robert V, Berindan-Neagoe, Ioana
Formáid: Artigo
Teanga:Inglês
Foilsithe: Dove Medical Press 2016
Ábhair:
Original Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113913/
https://ncbi.nlm.nih.gov/pubmed/27956838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S110719
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