Double gene siRNA knockdown of mutant p53 and TNF induces apoptosis in triple-negative breast cancer cells

Apoptosis is the major downregulated pathway in cancer. Simultaneous inhibition using specific small interfering RNA (siRNA) of two key player genes, p53 and TNF, is an interesting and feasible strategy when it comes to investigating various molecular pathways and biological processes in triple-nega...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Pileczki, Valentina, Pop, Laura, Braicu, Cornelia, Budisan, Livia, Bolba Morar, Gabriela, del C Monroig-Bosque, Paloma, Sandulescu, Robert V, Berindan-Neagoe, Ioana
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113913/
https://ncbi.nlm.nih.gov/pubmed/27956838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S110719
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