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Double gene siRNA knockdown of mutant p53 and TNF induces apoptosis in triple-negative breast cancer cells

Apoptosis is the major downregulated pathway in cancer. Simultaneous inhibition using specific small interfering RNA (siRNA) of two key player genes, p53 and TNF, is an interesting and feasible strategy when it comes to investigating various molecular pathways and biological processes in triple-nega...

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Bibliografiske detaljer
Udgivet i:Onco Targets Ther
Main Authors: Pileczki, Valentina, Pop, Laura, Braicu, Cornelia, Budisan, Livia, Bolba Morar, Gabriela, del C Monroig-Bosque, Paloma, Sandulescu, Robert V, Berindan-Neagoe, Ioana
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113913/
https://ncbi.nlm.nih.gov/pubmed/27956838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S110719
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