Double gene siRNA knockdown of mutant p53 and TNF induces apoptosis in triple-negative breast cancer cells

Apoptosis is the major downregulated pathway in cancer. Simultaneous inhibition using specific small interfering RNA (siRNA) of two key player genes, p53 and TNF, is an interesting and feasible strategy when it comes to investigating various molecular pathways and biological processes in triple-nega...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Pileczki, Valentina, Pop, Laura, Braicu, Cornelia, Budisan, Livia, Bolba Morar, Gabriela, del C Monroig-Bosque, Paloma, Sandulescu, Robert V, Berindan-Neagoe, Ioana
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113913/
https://ncbi.nlm.nih.gov/pubmed/27956838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S110719
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