Mirror‐Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide

Programs of drug discovery generally exploit one enantiomer of a chiral compound for lead development following the principle that enantiomer recognition is central to biological specificity. However, chiral promiscuity has been identified for a number of enzyme families, which have shown that mirro...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Angew Chem Int Ed Engl
Glavni autori: Bisson, Claudine, Britton, K. Linda, Sedelnikova, Svetlana E., Rodgers, H. Fiona, Eadsforth, Thomas C., Viner, Russell C., Hawkes, Tim R., Baker, Patrick J., Rice, David W.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Communications
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113775/
https://ncbi.nlm.nih.gov/pubmed/27717128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201607185
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items