Targeting Mll1 H3K4 methyltransferase activity to guide cardiac lineage specific reprogramming of fibroblasts

Generation of induced cardiomyocytes (iCMs) directly from fibroblasts offers a great opportunity for cardiac disease modeling and cardiac regeneration. A major challenge of iCM generation is the low conversion rate. To address this issue, we attempted to identify small molecules that could potentiat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Discov
Egile Nagusiak: Liu, Liu, Lei, Ienglam, Karatas, Hacer, Li, Yangbing, Wang, Li, Gnatovskiy, Leonid, Dou, Yali, Wang, Shaomeng, Qian, Li, Wang, Zhong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113048/
https://ncbi.nlm.nih.gov/pubmed/27924221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2016.36
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak