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MLL1 and MLL1 fusion proteins have distinct functions in regulating leukemic transcription program
Mixed lineage leukemia protein-1 (MLL1) has a critical role in human MLL1 rearranged leukemia (MLLr) and is a validated therapeutic target. However, its role in regulating global gene expression in MLLr cells, as well as its interplay with MLL1 fusion proteins remains unclear. Here we show that desp...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cell Discov |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4869169/ https://ncbi.nlm.nih.gov/pubmed/27462455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2016.8 |
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