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MLL1 Inhibition Reprograms Epiblast Stem Cells to Naïve Pluripotency

The interconversion between naïve and primed pluripotent states is accompanied by drastic epigenetic rearrangements. However, it is unclear whether intrinsic epigenetic events can drive reprogramming to naïve pluripotency, or if distinct chromatin states are instead simply a reflection of discrete p...

詳細記述

保存先:
書誌詳細
出版年:Cell Stem Cell
主要な著者: Zhang, Hui, Gayen, Srimonta, Xiong, Jie, Zhou, Bo, Shanmugam, Avinash K, Sun, Yuqing, Karatas, Hacer, Liu, Liu, Rao, Rajesh C., Wang, Shaomeng, Nesvizhskii, Alexey I., Kalantry, Sundeep, Dou, Yali
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826731/
https://ncbi.nlm.nih.gov/pubmed/26996599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.02.004
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