MLL1 Inhibition Reprograms Epiblast Stem Cells to Naïve Pluripotency

The interconversion between naïve and primed pluripotent states is accompanied by drastic epigenetic rearrangements. However, it is unclear whether intrinsic epigenetic events can drive reprogramming to naïve pluripotency, or if distinct chromatin states are instead simply a reflection of discrete p...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Zhang, Hui, Gayen, Srimonta, Xiong, Jie, Zhou, Bo, Shanmugam, Avinash K, Sun, Yuqing, Karatas, Hacer, Liu, Liu, Rao, Rajesh C., Wang, Shaomeng, Nesvizhskii, Alexey I., Kalantry, Sundeep, Dou, Yali
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826731/
https://ncbi.nlm.nih.gov/pubmed/26996599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.02.004
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