MLL1 Inhibition Reprograms Epiblast Stem Cells to Naïve Pluripotency

The interconversion between naïve and primed pluripotent states is accompanied by drastic epigenetic rearrangements. However, it is unclear whether intrinsic epigenetic events can drive reprogramming to naïve pluripotency, or if distinct chromatin states are instead simply a reflection of discrete p...

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Publicado en:Cell Stem Cell
Autores principales: Zhang, Hui, Gayen, Srimonta, Xiong, Jie, Zhou, Bo, Shanmugam, Avinash K, Sun, Yuqing, Karatas, Hacer, Liu, Liu, Rao, Rajesh C., Wang, Shaomeng, Nesvizhskii, Alexey I., Kalantry, Sundeep, Dou, Yali
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826731/
https://ncbi.nlm.nih.gov/pubmed/26996599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.02.004
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