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Targeted Genome Modification via Triple Helix Formation
Triplex-forming oligonucleotides (TFOs) are capable of coordinating genome modification in a targeted, site-specific manner, causing mutagenesis or even coordinating homologous recombination events. Here, we describe the use of TFOs such as peptide nucleic acids for targeted genome modification. We...
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| Pubblicato in: | Methods Mol Biol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5111905/ https://ncbi.nlm.nih.gov/pubmed/25030921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-0992-6_8 |
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