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Sequence-specific Triple Helix Formation with Genomic DNA

We have previously demonstrated site-specific delivery of antiparallel phosphorothioate triplex forming oligonucleotide (TFO) specific to −165 to −141 promoter region of α1(I) collagen (abbreviated as APS165) to hepatic stellate cells (HSCs) of fibrotic rats after conjugation with mannose 6-phosphat...

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Hlavní autoři: Ye, Zhaoyang, Guntaka, Ramareddy V., Mahato, Ram I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536773/
https://ncbi.nlm.nih.gov/pubmed/17845009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi700580y
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