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Nanoparticle for delivery of antisense γPNA oligomers targeting CCR5

The development of a new class of peptide nucleic acids (PNAs), i.e., gamma PNAs (γPNAs), creates the need for a general and effective method for its delivery into cells for regulating gene expression in mammalian cells. Here we report the antisense activity of a recently developed hydrophilic and b...

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Autori principali: Bahal, Raman, McNeer, Nicole Ali, Ly, Danith H., Saltzman, W. Mark, Glazer, Peter M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771998/
https://ncbi.nlm.nih.gov/pubmed/23954968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/adna.25628
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