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Spatial dynamics of SIRT1 and the subnuclear distribution of NADH species

Sirtuin 1 (SIRT1) is an NAD(+)-dependent deacetylase that functions as metabolic sensor of cellular energy and modulates biochemical pathways in the adaptation to changes in the environment. SIRT1 substrates include histones and proteins related to enhancement of mitochondrial function as well as an...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Aguilar-Arnal, Lorena, Ranjit, Suman, Stringari, Chiara, Orozco-Solis, Ricardo, Gratton, Enrico, Sassone-Corsi, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111721/
https://ncbi.nlm.nih.gov/pubmed/27791113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609227113
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