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Spatial dynamics of SIRT1 and the subnuclear distribution of NADH species

Sirtuin 1 (SIRT1) is an NAD(+)-dependent deacetylase that functions as metabolic sensor of cellular energy and modulates biochemical pathways in the adaptation to changes in the environment. SIRT1 substrates include histones and proteins related to enhancement of mitochondrial function as well as an...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Aguilar-Arnal, Lorena, Ranjit, Suman, Stringari, Chiara, Orozco-Solis, Ricardo, Gratton, Enrico, Sassone-Corsi, Paolo
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111721/
https://ncbi.nlm.nih.gov/pubmed/27791113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609227113
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