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Spatial dynamics of SIRT1 and the subnuclear distribution of NADH species

Sirtuin 1 (SIRT1) is an NAD(+)-dependent deacetylase that functions as metabolic sensor of cellular energy and modulates biochemical pathways in the adaptation to changes in the environment. SIRT1 substrates include histones and proteins related to enhancement of mitochondrial function as well as an...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Aguilar-Arnal, Lorena, Ranjit, Suman, Stringari, Chiara, Orozco-Solis, Ricardo, Gratton, Enrico, Sassone-Corsi, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111721/
https://ncbi.nlm.nih.gov/pubmed/27791113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609227113
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