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Spatial dynamics of SIRT1 and the subnuclear distribution of NADH species

Sirtuin 1 (SIRT1) is an NAD(+)-dependent deacetylase that functions as metabolic sensor of cellular energy and modulates biochemical pathways in the adaptation to changes in the environment. SIRT1 substrates include histones and proteins related to enhancement of mitochondrial function as well as an...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Aguilar-Arnal, Lorena, Ranjit, Suman, Stringari, Chiara, Orozco-Solis, Ricardo, Gratton, Enrico, Sassone-Corsi, Paolo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111721/
https://ncbi.nlm.nih.gov/pubmed/27791113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609227113
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