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Acid activation mechanism of the influenza A M2 proton channel

The homotetrameric influenza A M2 channel (AM2) is an acid-activated proton channel responsible for the acidification of the influenza virus interior, an important step in the viral lifecycle. Four histidine residues (His37) in the center of the channel act as a pH sensor and proton selectivity filt...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Liang, Ruibin, Swanson, Jessica M. J., Madsen, Jesper J., Hong, Mei, DeGrado, William F., Voth, Gregory A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111692/
https://ncbi.nlm.nih.gov/pubmed/27791184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615471113
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