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Acid activation mechanism of the influenza A M2 proton channel

The homotetrameric influenza A M2 channel (AM2) is an acid-activated proton channel responsible for the acidification of the influenza virus interior, an important step in the viral lifecycle. Four histidine residues (His37) in the center of the channel act as a pH sensor and proton selectivity filt...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Liang, Ruibin, Swanson, Jessica M. J., Madsen, Jesper J., Hong, Mei, DeGrado, William F., Voth, Gregory A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111692/
https://ncbi.nlm.nih.gov/pubmed/27791184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615471113
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