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Multiscale simulation reveals a multifaceted mechanism of proton permeation through the influenza A M2 proton channel
The influenza A virus M2 channel (AM2) is crucial in the viral life cycle. Despite many previous experimental and computational studies, the mechanism of the activating process in which proton permeation acidifies the virion to release the viral RNA and core proteins is not well understood. Herein t...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4084430/ https://ncbi.nlm.nih.gov/pubmed/24979779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401997111 |
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