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Proton Induced Conformational and Hydration Dynamics in the Influenza A M2 Channel

The influenza A M2 protein is an acid-activated proton channel responsible for the acidification of the inside of the virus, a critical step in the viral life cycle. This channel has four central histidine residues that form an acid-activated gate, binding protons from the outside until an activated...

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Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Watkins, Laura C., Liang, Ruibin, Swanson, Jessica M.J., DeGrado, William F., Voth, Gregory A.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768079/
https://ncbi.nlm.nih.gov/pubmed/31264413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b05136
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